4(1H)-Pyrimidinone, 6-amino-
4-Amino-6-hydroxypyrimidine
CAS: 1193-22-2
Molecular Formula: C4H5N3O
4(1H)-Pyrimidinone, 6-amino- - Names and Identifiers
4(1H)-Pyrimidinone, 6-amino- - Physico-chemical Properties
| Molecular Formula | C4H5N3O |
| Molar Mass | 111.1 |
| Density | 1.55±0.1 g/cm3(Predicted) |
| Melting Point | 262-264°C |
| Boling Point | 227.5±43.0 °C(Predicted) |
| Flash Point | 91.4°C |
| Solubility | DMSO |
| Vapor Presure | 0.0772mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| BRN | 112429 |
| pKa | 10.04±0.40(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.688 |
| MDL | MFCD00051502 |
4(1H)-Pyrimidinone, 6-amino- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| Hazard Class | IRRITANT |
4(1H)-Pyrimidinone, 6-amino- - Introduction
4-Amino-6-hydroxypyrimidine, also known as 4-aminouracil-6-ol, is an organic compound. Its molecular formula is C4H6N2O2 and its relative molecular mass is 114.10g/mol.
Regarding the properties of 4-amino-6-hydroxypyrimidine, it is a colorless crystalline solid with a sweet taste. It is stable at room temperature and can be dissolved in water.
The main use of 4-amino-6-hydroxypyrimidine is as a reagent and intermediate in biochemical research. It can be used as a precursor for the synthesis of nucleotides and nucleic acids for research and development in the field of biomedicine. In addition, it can also be used for the preparation of agricultural plant growth regulators.
One method for preparing 4-amino-6-hydroxypyrimidine is synthesis through amination reaction. Specifically, one of the commonly used methods of preparation is to react uracil with an aminating agent and heat the reaction under alkaline conditions. After the reaction, a pure product was obtained by steps such as crystallization, filtration, and washing.
Regarding safety information, 4-amino-6-hydroxypyrimidine is considered relatively safe under normal use and storage conditions. However, any chemical should be handled with caution when used. It is recommended to follow laboratory safety practices, including wearing appropriate protective equipment (such as gloves and glasses), avoiding contact with skin and eyes, and avoiding inhalation of dust or solutions. In an emergency, seek help from a medical professional immediately.
Regarding the properties of 4-amino-6-hydroxypyrimidine, it is a colorless crystalline solid with a sweet taste. It is stable at room temperature and can be dissolved in water.
The main use of 4-amino-6-hydroxypyrimidine is as a reagent and intermediate in biochemical research. It can be used as a precursor for the synthesis of nucleotides and nucleic acids for research and development in the field of biomedicine. In addition, it can also be used for the preparation of agricultural plant growth regulators.
One method for preparing 4-amino-6-hydroxypyrimidine is synthesis through amination reaction. Specifically, one of the commonly used methods of preparation is to react uracil with an aminating agent and heat the reaction under alkaline conditions. After the reaction, a pure product was obtained by steps such as crystallization, filtration, and washing.
Regarding safety information, 4-amino-6-hydroxypyrimidine is considered relatively safe under normal use and storage conditions. However, any chemical should be handled with caution when used. It is recommended to follow laboratory safety practices, including wearing appropriate protective equipment (such as gloves and glasses), avoiding contact with skin and eyes, and avoiding inhalation of dust or solutions. In an emergency, seek help from a medical professional immediately.
Last Update：2024-04-09 21:54:55
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CAS: 1193-22-2
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CAS: 1193-22-2
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